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These changes could sensitise the trigeminal vascular system, which is considered to play a major role in the physiopathology of migraine.
Moreover, we investigated whether XIAP downregulation could sensitise ovarian CCC cells to platinum agents.
Chemotherapy and/or radiation could sensitise TRAIL-induced apoptosis in vitro as well as in vivo.
Thus, it is possible that GA could sensitise CDDP in NSCLC by promoting apoptosis.
This observation strongly suggests that bortezomib could sensitise cancer cells to EGFR inhibition.
Zhang et al (2012) reported that miR-513a-3p miR-513a-3p miR-513a-3pung adenocouldnoma cellsensitiselatin by targeting GSTP1.
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Although animals might habituate to continuous exposure to the same noise [11], variable or unpredictable exposure or the occurrence of novel noise may prevent this (for example, three freshwater fish species show cortisol responses to variable boat noise but not to continuous Gaussian noise [12]) and could even sensitise them to such disturbances.
However, even this additional stressor could not sensitise SiHa cells to increased cytolysis by the combined action of TNF-α and histamine.
Although our data should be interpreted with care, to our knowledge they represent the first evidence of mechanisms that could possibly sensitise tumour cells to oestrogen stimulation in response to aromatase inhibition in vivo.
In contrast, HDACIs could not sensitise NB cells to low doses of classical chemotherapeutic drugs, such as Doxorubicin, Taxol, Cisplatin or Etoposide, except for a very weak sensitisation observed when DOX was combined with TSA (data not shown).
Nerve fascicles containing sensory afferents are present in tendons and especially in the peritendinous tissue; these nerves express receptors for the nociceptive substances which could thereby sensitise the nerves and augment pain signalling.
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