Sentence examples for Confirmatory trial from inspiring English sources
The confirmatory trial results clearly indicate that the setting time and CCS at different ages targeted were achieved using design of experiments.
To gather information for a future confirmatory trial of dobutamine (DB) for circulatory impairment (ie, low superior vena cava [SVC] flow).
Although cTBS proved a safe procedure, on the basis of the present findings a larger randomized confirmatory trial seems unjustified in ALS patients, at least in advanced stage of the disease.
A confirmatory trial of the Tenofovir gel is underway, and if successful the vaginal gel could fill a gap in HIV prevention for women who may not be able to insist on condoms or faithfulness from their partners.
The goal of most POC trials is to determine whether a treatment is likely to be efficacious for a given indication and thus whether it is worth investing the financial resources and participant exposure necessary for a confirmatory trial of that intervention.
We consider the problem of designing a confirmatory trial when the biological hypothesis of the experimental therapy is strongly supported by the pre-clinical data but limited clinical data is available to pre-define a subpopulation based on a biomarker with continuous values.
"And these companies are just never going to do the confirmatory trials when only a couple of hundred people have the disease," she said.
Therapeutic trial designs need to take account of duration of treatment, dose response relationships and confirmatory trials.
We give an overview of the developments and associated statistical methods in several classes of adaptive designs of confirmatory trials.
We must accept that there are some uncertainties that remain when both exploratory and confirmatory trials are designed.
Evaluating candidate biomarkers in the exploratory phases of drug development and investigating surrogate endpoints in confirmatory trials require the establishment of a statistical and inferential framework.
