Sentence examples for Confirm receptor from inspiring English sources

To confirm receptor blockade, mice were administered 1 mg MIH5 or MAC219 via the i.p. route, followed by euthanasia at 24 h, and immediate ex vivo staining of the splenocytes.

Small-angle X-ray scattering measurements of human haptoglobin haemoglobin bound to the ligand-binding fragment of CD163 confirm receptor binding in this area, and show that the rigid dimeric complex can bind two receptors.

This high concordance between TGP and central IHC status, especially in the HER2 and ER groups, suggests that the PCR-based assay is a reliable surrogate for central IHC to confirm receptor status.

Considering this, we treated cells with ATP after removal of extracellular Ca2+ to evaluate Ca2+ release from internal Ca2+ stores, followed by the restoration of extracellular Ca2+ to confirm receptor activation-mediated extracellular Ca2+ influx.

cAMP was also quantified in HEK293 cells stably transfected with the pCMV-GFP (vector expressing green fluorescent protein) to confirm receptor expression and the results for cAMP accumulation were equivalent to the peptide assay negative controls indicating that the vector construct in the cells did not interfere with cAMP production.

Receptor blocking experiment was carried out to confirm receptor-mediated endocytosis of Tf-C-SLN.

Starting from the confirmed receptor genes in the T. nigroviridis genome, all Ensembl Gene IDs for genes positioned four megabases on each side of the receptor genes were downloaded and saved in an Excel file.

A murine tumor model of mice bearing an α5 β1-positive human colon carcinoma (RKO) on the one flank and an α v β3-positive human melanoma (M21) on the other flank confirmed receptor specific uptake and allows visualization of the α5 β1-positive tumor only.

Results: The static PET image of [68Ga]FSC succ-RGD 3 in nude mice showed highly visualized tumors of M21 (positive) whereas nonvisualized tumor of M21-L (negative) tumor xenografts 1 h post injection confirming receptor-specific activity accumulation.

Cell uptake studies using human melanoma M21 (αv β3-positive and α5 β1-negative), human melanoma M21-L (αv β3-negative and α5 β1-negative), and human prostate carcinoma DU145 (αv β3-negative and α5 β1-positive) confirmed receptor-specific binding.

Corresponding signal values were found to confirm homogenous receptor expression within the whole binding experiment (Fig. 6c).