We concluded this variant was not likely contributing to this patient's PCD phenotype and this case remained unsolved.
This polymorphism is associated with accelerated tumour formation in both hereditary and sporadic cancers (for a review see Bond and Levine, 2007) and a meta-analysis recently concluded that variant homozygote G/G was associated with a significantly increased risk of all types of tumours (Hu et al, 2007).
They concluded that variants in the neuronal NO synthase gene contribute to the variability of airway NO concentrations in healthy females.
From the data obtained by Edman degradation analysis it could not be concluded which variants of polymorphic salivary proteins were present in the proteome.
We therefore concluded that variants within the XRCC4 gene might confer genetically reduced susceptibility to colorectal cancer among patients with schizophrenia.
Previous experiments conducted by Dale et al. on 3 serotypes included in the 26-valent GAS vaccine found that slight allelic variants had little influence on bactericidal killing activity during in vitro assays, leading the researchers to conclude that variant subtypes might not affect vaccine efficacy (27 ).
We conclude that variant patterns of hypsarrhythmia are frequent, generally do not correlate with prognosis, and thus are best included within the definition of hypsarrhythmia.
These results allow us to conclude that variant 4C7 induces a much faster and robust initiator and effector caspase activation than rhTRAILWT in the OVCAR-3 cell line, and underlines the efficacy of the DR4-specific variant.
The variant opsins were, however, less stable than wild type.It is concluded that the variant L opsin haplotypes underlie BED.
If the mother's patterns of genetic variants, or haplotypes, are known, statistics allow researchers to conclude what variants she passed on to her offspring.
We conclude that variants in TREH control trehalase activity, and although one of these variants is also reproducibly associated with T2D, it is likely that the effect of the SNP on risk of T2D occurs by a mechanism different than affecting trehalase activity.
