This leads to a challenging bi-objective constrained optimization problem, which relies on a computationally expensive intricate process-modelling simulator of the DWPP and has to be solved with limited computational budget.
The popularity of the Naïve-Bayes as a target-fishing tool can be probably attributed to the fact that building non-Naïve Bayes multi-class classifiers (be probabilistic or not) can become conceptually intricate or computationally demanding, or both [10, 11, 17 19, 22 24, 33 37].
The work presented here explores a biologically-motivated multi-resolution speaker information representation obtained by performing an intricate yet computationally-efficient analysis of the information-rich spectro-temporal attributes of the speech signal.
Simulation of the cochlea is computationally challenging due to its complex geometry, intricate construction and small physical size.
However, this approach might be computationally demanding and, hence, the study of intricate reaction networks might become infeasible.
By computationally sorting out different conformational states and reconstructing the structures from well-defined populations, the resulting 3D structures are considerably more intricate and provide new information for the Mediator structural organization, although the nominal resolution of the 3D reconstructions was not higher (Supplementary information, Figure S2) than that in previous studies.
With the help of computationally-intensive searches, there have been several studies that have claimed to demonstrate the existence of surprisingly precise and intricate patterns of repeating activity in neuronal circuits from in vivo preparations [7] [13], intact slices [1], [7], [14], [15], dissociated neuronal cultures [16] [18], and sophisticated neuronal models [19] [21].
(Those were intricate times).
The backstory is intricate.
It was intricate and exponential.
