Sentence examples for Compromised functionality from inspiring English sources

In this scenario, which remains to be tested, complex I deficiency could be explained by decreased expression levels of correctly spliced NUBPL, in combination with mildly compromised functionality due to the missense mutation.

The penumbra region retains structural integrity but has a compromised functionality and its long term recovery defines the basis for stroke and/or tissue infarction therapy (Yuan, 2009).

EC JAM-C-KO mice also showed slower tumor growth, as well as reduced pericyte coverage and compromised functionality of tumor blood vessels.

With the discussed concepts in mind that the conserved cysteine might be crucial for a possible redox-regulation of Pex5p and PTS1-protein import [ 52, 53], the polyubiquitination of Pex5pC6K observed by us might simply indicate a compromised functionality of Pex5p without its supposed redox-sensor.

Critically, its designers were also unafraid to compromise functionality in pursuit of this concept.

Further, to achieve covalent linking, cargoes are chemically modified, which may compromise functionality.

Sequences with functional activity are subject to selective pressures that prevent the fixation of mutations that would compromise functionality.

The molecular functionality of such structures can no longer be assumed to be optimal, as slightly deleterious mutations may have compromised functional integrity [ 10, 99- 102].

Describing the plane, already more than 20 years old, as "awe inspiring", he extolled its style and beauty, noting that this had never compromised its functionality.

Here, using stable transfected SH-SY5Y cells overexpressing APP751wt (SY5Y-APP) we demonstrated that the expression of an unfolded p53 conformation compromised neuronal functionality.

The formulation of micronutrients and nutraceuticals in the design of functional foods and beverages brings enormous technological challenges because often this can compromise product functionality.