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Clinical determination of the outer limits of the optic disk (OD) doesn't always correspond to the true anatomic limits of the optic nerve head (ONH) defined by the Bruch's membrane opening (BMO).
Clinical determination of apical canal anatomy is difficult.
Clinical determination of mid-parental height is an important part of the assessment of a child's growth, however our clinical impression has been that parents cannot be relied upon to accurately report their own heights.
Decisions about whether licensing restrictions are necessary to ensure safety of the traveling public are ultimately determined by the licensing agency, taking into account the clinical determination of medical fitness.
If ER or HER2 status were not reported, they were determined by array, but preference was given to studies with clinical determination first.
Dyslexic individuals were diagnosed by the doctors' clinical determination.
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While the PHQ-9 is a self-report measure, self-report has been shown to be highly associated with clinical determinations.
In cases when interpretation cannot be independently verified, payers would be on firm ground to request – or demand – the evidence underlying the clinical determinations.
Another project currently in progress is comparing the classification of the five conventional clinical biomarkers (clinical determinations for ER, PgR, HER2, Ki67, and histological grade) to paired classifications based on RNA-seq gene expression signatures.
Jon Tyson's [ 22] and Terri Major-Kincade and colleagues' [ 17] work on clinical determinations of whether or not to treat severely disabled premature newborns enlist this use of the term "evidence-based bioethics", which I read to be a more accurate interpretation of the term because of its consistency with the methods of evidence-based medicine.
One of the most daunting problems encountered when evaluating an S. Typhi vaccine is making a pre-clinical determination of its safety and/or level of attenuation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com