Sentence examples for Circumvent the challenges of from inspiring English sources

To circumvent the challenges of in vitro and in vivo expansion of hMSCs, several ex vivo systems have been proposed.

Because they circumvent the challenges of a priori selection of particular regions in clinical trials, these novel methods may become useful tools in DMOAD trials [ 29].

This approach may circumvent the challenges of previous clinical trials based on organ of origin recruitment, in which there have been mixed results but some efficacy in individuals (see Additional file 11).

Numerous other reports (see Table  1) have also used a two-step click chemistry-mediated labeling approach to circumvent the challenges of designing a bulky synthetic probe capable of binding in the active site of GH enzymes akin to native ligands; these probes incorporate either an azide or alkyne for the click chemistry reaction.

To circumvent the challenge of ascertaining RNA expression in infected cells with waning levels of housekeeping genes, real-time PCR was performed using primers specific for the cPMLΔ5&6 transcripts along with primers that recognize all PML isoforms (primers derived from exon 3) to compare the expression of cPMLΔ5&6 to total PML transcripts during viral infection.

Different sequence alignment software packages have attempted to circumvent the challenge of assigning reads that map to multiple sites (termed multi-reads) [ 24- 29].

A recent approach to circumvent the challenge of tumor heterogeneity and to extract meaningful data from formalin-fixed tissue blocks has been suggested, combining matrix-assisted laser desorption ionization (MALDI) with imaging (MALDI imaging mass spectroscopy; MALDI-IMS).

While this intermediate resistance mechanism remains to be validated in the clinical setting, it raises the possibility of suppressing pre-conditions that favor the acquisition of drug resistance, in order to circumvent the challenge of treating multiple established drug-resistant pathways.

To circumvent the challenge of defining housekeeping genes that would reliably scale with the size of the adult retina across sexes and species, we measured the relative expression of rh3 mRNA to the expression of rh3 and rh4 combined (rh3:rh3 + 4, the rh3 index, Figure  5A), and the relative expression of rh5 mRNA to the expression of rh5 and rh6 combined (rh5:rh5 + 6, the rh5 index, Figure  5B).

Now you circumvented the challenges of everything.

This approach circumvents the challenge of the strong electrostatic interactions at the RIPSRL interface.