Based on this target-triggered highly efficient DNA nanoassembly and DNAzyme-modulated double quenching mechanism, the proposed biosensing strategy showed admirable signal amplification capability.
Based on this, targeting tumoral HIF-1α is under intense investigation as a therapeutic target for cancer chemotherapy.
Based on this, targeting tumoral HIF-1α is under intense investigation as a therapeutic strategy to inhibit angiogenesis and tumor growth.
This review covers the main aspects concerning structural and functional features of the flavivirus C protein, ultimately, highlighting prospects in drug discovery based on this viral target.
The present findings regarding the correlation of PRDM16 polymorphism with lean body mass provide a promising new direction for the clinical management of sarcopenia that could lead to the development of new diagnostic markers as well as therapeutic options based on this molecular target.
Based on this evidence, targeting proteasomes might decrease NF-κB activity and thus be a useful strategy in AIPC intervention.
Based on this scenario, targeted NGS of a broad panel of NS-related genes has emerged as a cost-effective strategy to screen the multiple genes involved in SRNS/FSGS, but optimal sensitivity and specificity must be demonstrated for each gene in the panel.
