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To ensure that the PP and SC are independently activated by electrical stimulation with electrodes placed at stratum radiatum (SR) and stratum lacunosum-moleculare (SLM), we used paired-pulses or tri-pulses to deliver stimuli at SC-PP or PP-SC.
In previous studies, we showed that the coupling of weak patterned stimulation of the Schaffer collateral (SC) input to CA1, with exploration of spatial constellations of small objects positioned in holeboard holes, results in lasting LTD at stratum radiatum synapses (Manahan-Vaughan and Braunewell 1999; Kemp and Manahan-Vaughan 2004; Lemon and Manahan-Vaughan 2006).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com