Sentence examples for At prc from inspiring English sources

The range of expression levels at PRC targets suggests that PRCs do not act as absolute silencers, but may regulate the extent of RNAPII transcriptional activity, as described in Drosophila (Enderle et al., 2011; Schwartz and Pirrotta, 2008).

The presence of PRCs, RNAPII-S5p, and repressive/active histone marks at PRC targets in ESCs has been seen after population-based ChIP assays (Alder et al., 2010; Bernstein et al., 2006; Mikkelsen et al., 2007; Stock et al., 2007).

[C4.] Julie Huff, a systems architect at PRC, and two colleagues have received a patent for a computer platform designed to allow businesses or the military to track digital marauders as they are trying to hack into a system.

But Julie Huff, a systems architect at PRC, a division of the military contractor Northrop Grumman, thinks that in this age of information warfare computers should not simply close the portcullis when threatened.

In 1945, while at PRC, he directed one of the all-time noir cult classics, Detour.

To explore the range of expression states at PRC targets, we mapped RNAPII presence and modification across the ESC genome.

Lack of coassociation between PRCs and S2p thus supports an "on-off" (digital) switch mechanism of PRC regulation, where PRC impedes establishment of active RNAPII at PRC-bound chromatin.

At active PRC targets, PRCs are also tightly interlinked with unproductive RNAPII-S5p complexes.

Studies of RNAPII modification at PRC-target genes in ESCs have been limited.

To directly test whether RNAPII and PRCs simultaneously coassociate at PRC-repressed chromatin, we used sequential ChIP (re-ChIP).

The RNAPII configuration identified at PRC-repressed genes does not simply reflect uniformly lower RNAPII abundance (with a lower detection threshold for S2p than S5p).