Sentence examples for At ppi from inspiring English sources

Therefore, future research directed at PPI target discovery, PPI interface characterization, and PPI-focused chemical libraries are expected to accelerate the development of the next generation of PPI-based anticancer agents.

From the initial discovery of the existence of hot spots at PPI interfaces, it has been proposed that hot spots might provide the key for developing small-molecule PPI inhibitors.

This piece has also been published at PPI's new website The Progressive Fix.

Here we provide a unique prospective for prioritizing drug targets for infectious diseases by looking at PPI targets, rather than single proteins.

We are unable to get a clear testimony to sustain this relationship by looking at PPI database.

Compounds were then developed and were shown to block the binding of an α-helix peptide from FtsZ.[ 15] Fesik and colleagues recently used a fragment-based approach to develop small molecules that prevent Sos binding to K-Ras by binding at a surface site of K-Ras.[ 16] Despite these successes, identification of fragments at PPI sites is not always possible.

On the other hand, the lower LEs typically associated with small molecule binding at PPIs raise the barrier to the detection of bona fide low-affinity fragment hits.

The iPhone 6 Plus has a 5.5", 1920×1080 LTPS TFT LCD at 400 ppi; the panel suppliers are LG Display and Japan Display.

The iPhone 6 uses a 4.7", 1334×750 LTPS (low temperature polysilicon) TFT LCD at 326 ppi (pixels per inch); the panel suppliers are LG Display, Japan Display and Sharp.

Its 2560 x 1440 resolution comes in at 216 PPI.

The Nexus 5X sports a 5.2 inch, FHD (1920 x 1080) LCD at 423 ppi screen.