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At its outbreak in 1936, defending the Spanish republic defined choices for a generation; and when it ended three years later in victory for General Franco's Nacionales, Spain was politically frozen for almost 40 years.
The second Palestinian intifada began in September 2000 against the backdrop of a viable political peace process, and it was not restrained by Yasir Arafat at its outbreak.
Even at its outbreak in 1775 British attitudes to the American war were mixed.
Unprepared by what historian Max Nettlau called the "explosive imminence" of the First World War at its outbreak in August 1914, anarchists resigned themselves to the reality of the situation and, after a time, began themselves to take sides.
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Coup apologists of all stripes--especially at its outbreak--had all sorts of justifications.
China has been fighting the disease with quarantines for months, while Vietnam swiftly quarantined its outbreak at the French Hospital in Hanoi on March 11.
Cholera has spread at a rapid pace since its outbreak in April.
But even at its peak, the outbreak was not as disruptive in Guinea, so people kiss and shake hands with no fear of catching the virus.At times last year it looked as if Ebola was under control in Guinea, the largest of the affected countries.
The federal government can also help ensure that communities are able to use modern data collection and analysis to detect a possible disease outbreak at its earliest stages in order to provide medical care swiftly.
"We know that the best way to protect Americans from Ebola is to stop the outbreak at its source," he said on Wednesday.
As Morse points out, diagnostic tests are especially important for tackling the outbreak at its source West Africa.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com