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Since both groups are similar at baseline by design, the marginal expectation of the response depends only on a group effect (MTX vs. PBO), a quadratic time trend specific to each period (in order to capture the natural evolution over time), and the DAS44 at baselines (T0 and T +5, see Figure 1), and an interaction period - treatment group [ 16].
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A prophylaxis was performed at baseline.
Groups were well matched at baseline.
Each listener provided pretraining ratings at baseline.
At baseline MEDAS points were ~8.5.
Potential risk factors were assessed at baseline.
Lean body mass was decreased at baseline.
All patients had diastolic dysfunction at baseline.
Table 1 Participant characteristics at baseline: Mean (n), unless stated.
Tumour measurements were performed at baseline and every 8 weeks.
(A) Circulating GLP-1 level at baseline, P>0.05.
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