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To identify drugs that have activity against B. burgdorferi persisters, we used stationary-phase B. burgdorferi as a persistence model (see above section) to screen an FDA-approved drug library.
Thus, although escape from CD8+ T cell recognition is recognized as a persistence mechanism during acute infection [30], the earliest samples analyzed here were generally taken several years after infection, when escape mutations likely have occurred and become fixed in the viral population infecting a given host [30].
Hasan et al. [ 15] similarly scored relA low as a persistence target.
The venous return from the lower body will not pass through an intrahepatic portion of the inferior vena cava, but will develop as a persistence of some other embryonic venous pathway, usually as a vena azygos continuation.
Clinical failure was defined as a persistence or progression of clinical symptoms of infection, initial recovery followed by deterioration, change in wider spectrum antibiotic therapy (escalation), increased radiological infiltrates and/or worsening of laboratory data.
The key findings of this study demonstrate that de novo adolescent ethanol exposure through either social interaction with an intoxicated peer or direct experience with the drug both yield an enhanced behavioral response to ethanol odor in adolescence as well as a persistence of these alterations into adulthood.
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Five studies defined treatment failure as either a persistence of fast breathing after 3 5 days or disease progression (development of LCI or danger signs) between 1 5 days after antibiotic initiation.
Surprisingly, the odds of sprouters becoming locally extinct were the same as non-sprouters, despite sprouters being widely regarded as representative of a persistence niche [35].
However, there is no ambiguity when representing the intervals as points in a persistence diagram (see Figure 5(d)).
Whereas Hibernate and the Enterprise Java Beans specification provide sufficient authentication and authorization functionalities in the context of object persistence, the Java Data Objects (JDO) specification designed as a lightweight persistence approach doesn't provide any declarative security capabilities.
Sliding in almost as a whisper, with a persistence that has surprised many in Hollywood, a $17 million Gothic horror film called "The Others" lasted in the weekend box office Top 10 for nine weeks until finally slipping out this weekend.
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