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On other hand, many amino acids (ALA, ASP, CYS, GLN, GLU, ILE, LEU, MET, PHE, PRO, and VAL) are disfavoured in the interactions sites.
Amino acid substitution models such as PAM [31] and BLOSUM [32] describe the degree of substitutions as log-odd ratio values where the positive scores suggest commonly occurring and preferred substitutions, whereas the negative scores imply very rare substitutions which are disfavoured in nature.
Thus, it appears that thelytokous lineages producing a noteworthy proportion of diploid male offspring are disfavoured by selection, as expected [ 85].
Finally, there is no theoretical basis for the assumption that CPs are disfavoured because of their negative effects on translation efficiency and this concept runs counter to our growing understanding of the intricate mechanisms that govern gene expression.
Because of its potential effect on gene expression, altering CP frequencies towards those that are disfavoured in their hosts has recently been advocated as a novel strategy to reduce RNA virus replication (Coleman et al., 2008; Wimmer et al., 2009; Mueller et al., 2010; Martrus et al., 2013; Yang et al., 2013; Le Nouen et al., 2014; Ni et al., 2014).
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Major depressive disorder and depression severity are socially patterned, disfavouring individuals from lower socioeconomic groups.
Histone methylations associated with heterochromatic conformations are, on the other hand, disfavoured by MLV vector integrations.
Are coronal loops isothermal?
ARE Conf.
Are fish?
Are trajectories flexible?
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