Even with the substantial resources and considerable effort applied to providing instructions in lifestyle modification, observations suggest that the effectiveness for lifestyle intervention wanes over time.
It has been shown that qPCR results are highly dependent on the reference genes chosen [ 6], which explain the considerable effort applied into the validation of the gene(s) selected for the normalization stage, prior to extensive experimentation [ 7].
Over recent years considerable effort has been applied to understand these aspects and that progress is reported here along with some of the difficulties encountered in defining the behaviour.
Thus, considerable effort has been applied toward development of reliable methods for ENM toxicity assessment.
In the fields of solid state lighting, integrated circuits based on organic field-effect transistors (OFETs 7,8,9,10,11 and organic photovoltaic cells (OPVCs 12,13,14,15,16, commercial breakthrough is still ahead, with considerable effort in fundamental as well as applied research currently undertaken.
Organic light-emitting diodes (OLEDs) have been successfully commercialized in the mobile phone market, and considerable effort is currently being devoted to applying OLEDs in other commercial applications such as televisions (TVs) and lighting.
"It is apparent that the person(s) behind the Satoshi name accumulated a not insignificant knowledge of applied cryptography," he wrote, adding that the design was "elegant" and required "considerable effort and dedication, and programming proficiency".
Gasquet's triumph came with considerable effort.
But it was movement with considerable effort.
It takes time, patience and considerable effort.
As previously stated, considerable effort goes into search engine optimisation.
