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JJP and NJC conceived of, carried out, and interpreted the bioinformatics analyses.
ZH is an employee of, and NJC and ERP have received financial support from, Pfizer Inc.
MB and NJC were supported by the Wellcome Trust [grant WT 085775/Z/08/Z].
SDB, AT, JP, KGK and NJC conceived and designed the study; NJC, SRH and KGK analysed the data.
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NJC, JP and SDB conceived the project; NJC performed the experiments; NJC and GSV analysed the data; NJC and SDB wrote the manuscript.
Possible effects of velocity and displacement on the NJC and number of submovements were also examined by comparing groups using general linear models with velocity and displacements as covariates.
SVG, NJC, and SL conceived of and designed the overall experimental approaches.
NJC and JCM established the neuropathological diagnoses and gradings.
NJC and JSC drafted the manuscript.
TFS, TEH, NJC, and AJG assisted in the anatomical annotation.
NJC and SL are co-corresponding authors of this work.
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