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MG thanks Department of Science and Technology (DST), Govt. of India and ICGEB, VSC thanks Department of Biotechnology, Govt. of India and SR thanks DST for support.

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These EST sequences were made available by our collaborators in International Center for Genetic Engineering and Biotechnology (ICGEB), New Delhi and University of Hyderabad, Hyderabad, India.

Frozen samples were transported to the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi, and kept in liquid nitrogen until thawed for cytoadherence assays.

Mice were housed and handled according to institutional guidelines, and experimental procedures approved by the International Centre for Genetic Engineering and Biotechnology (ICGEB) board.

This work is based upon research supported by the International Centre for Genetic Engineering and Biotechnology (ICGEB), South African Research Chairs Initiative of the Department of Science and Technology and the National Research Foundation, the South African Medical Research Council and the University of Cape Town.

Mice were housed and handled according to institutional guidelines, and experimental procedures approved by the International Centre for Genetic Engineering and Biotechnology (ICGEB) board, with full respect to the EU Directive 2010/63/EU for animal experimentation.

C57BL/6 and PD-1 deficient mice (obtained from Dr. Tasuku Honjo, Yoshida-konoe, Sakyo-ku, Kyoto University, Japan, via Dr. Megan Sikes, Transplantation Biology Research Center, Harvard Medical School, Boston, MA, USA) on a C57BL/6 background were bred in our specific pathogen-free animal facility at International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

Prof. Sandor Pongor, International Centre for Genetic Engineering and biotechnology (ICGEB), Italy Accepted.

This work was supported by internal grants from the International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

Prof. Sandor Pongor, International Centre for Genetic Engineering and biotechnology (ICGEB), Italy The written English of the manuscript could be further improved.

This work was supported by the Short-Term Fellowship (Ref. No. F/ROM11-02 F/ROM11-02warded through the International Center of Genetic Engineering and Biotechnology (ICGEB).

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