Sentence examples similar to Analytical phenotyping from inspiring English sources
A novel analytical approach (COrrelated Phenotypes for On-Target Effects; COPOTE) was used to discern probable on-target knockdown, based on identifying different shRNAs targeting the same gene and displaying concordant phenotypes across cell lines.
High-confidence on-target shRNAs/phenotypes were identified using a new analytical approach (COrrelated Phenotypes for On-Target Effects; COPOTE), based on finding two or more different shRNAs targeting the same gene and displaying concordant enrichment/depletion profiles across the cell lines (Pearson correlation).
Tianxi Cai is a major player in developing analytical tools for EHR phenotyping and predictive modeling with biomedical data.
FC can be engaged for both synthetic and analytical applications of complex phenotypes within a single species, multispecies, and microbial-library populations.
However, in-depth research into the BBB's phenotype demands higher analytical complexity than functional vs. pathological BBB; criteria which biomarker based BBB permeability analyses do not meet.
In this paper we review the literature on genotype-phenotype studies and analytical techniques focusing on MTB as an example.
Furthermore, such approaches require relatively large cohorts and place significant demands on the analytical approaches used to molecularly phenotype individuals.
Holmes et al [ 51] used a large-scale exploratory analytical approach to investigate metabolic phenotype variation across and within four human populations, based on 1H NMR spectroscopy.
This variability is a result of inconsistencies in the analytical methods, varied definitions of phenotype, frequent lack of replication, and occasional lack of reported allelic frequencies and/or relative risks.
In order to determine whether statistically significant differences in predictive capability between models exist, we performed paired t-test analyses of correlations (between DGV and phenotypes) for all analytical models across the 20 bootstrap replicates for each best-fit model (Table 5).
