Fish retina and tectum, and fly optic lobe, develop from a partitioned, unidirectionally proliferating neurectodermal domain that combines slowly dividing neuroepithelial stem cells and rapidly amplifying progenitors with shared genetic signatures to generate large numbers and different types of neurons in a temporally ordered way.
The labelling dynamics imply that transit amplifying cells are rapidly replaced from within the JZ.
Overall, differential expression of TgAP2 is not extensive between tachyzoite and merozoites, and this may reflect their similar life cycle fate as rapidly amplifying asexual stages.
A pulse of BrdU is followed by a chase period, when slowly cycling cells retain the BrdU label and transient amplifying cells proliferate rapidly and dilute the label.
Knowledge of the involvement of vertebrate species as reservoirs or amplifying species can rapidly affect the level of risk attributed to an emerging disease.
TA cell undergoes a limited number of rapidly amplifying cell division cycles to increase the cell population derived from a single PSC before leaving the proliferative compartment to produce intermediate cell [ 106].
Transient amplifying cells are more rapidly cycling, and after dividing for a limited period of time cease to proliferate and undergo terminal differentiation while moving towards the skin surface [ 4].
There, quiescent NSCs proliferate slowly, but they can become activated and give rise to an intermediate population of fast-dividing transient amplifying progenitor cells, which rapidly differentiate to neuroblasts, which can also proliferate (Urban & Guillemot, 2014).
Stem cells separated from their niche lose their stemness, although such a loss may be reversible, becoming 'transit-amplifying cells' that are rapidly proliferating but have a more limited proliferative potential, and can give rise to terminally differentiated cells.
Transit-amplifying cells can expand rapidly, providing progeny that differentiate into mature cells of varying lineages.
So when the winning VFX team's speech mentioning this was overdubbed by the rapidly-amplifying theme from Jaws, it made their shout-out seem censored for content rather than time-pressure.
