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Allelic variant 2 is an insertion of 12 nucleotides starting at position -78 of the canine Cox-2 gene (CGCCTCCGCCTC).
Allelic variant showed no correlation with FOXP3 protein expression (P = 0.792, rho = −0.046).
Arechiga, A.F. et al. Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling.
Genetic drift can lead to the fixation of a particular allelic variant in a population without any selective pressure.
Brockington, M. et al. Mutations in the fukutin-related protein gene (FKRP) identify limb girdle muscular dystrophy 2I as a milder allelic variant of congenital muscular dystrophy MDC1C.
Pallet, N. et al. Kidney transplant recipients carrying the CYP3A4*22 allelic variant have reduced tacrolimus clearance and often reach supratherapeutic tacrolimus concentrations.
CHA0/c2 carries the plasmid pME6031-cmp2 that contains an allelic variant (competitor) of the Pf153 specific sequence Pf153_2.
It is similar to the CfEG3a described earlier (Zhang et al., 2009) but not likely an allelic variant.
The first, copy-cutting involves a Cas9-gRNA complex selectively cutting one allelic variant, followed by homology-directed repair (HDR -mediated repair and replacement witHDR -mediatedable allele of the same gene prepaird in-trand.
Human TAS2R16 alone has at least 17 polymorphisms, including an allelic variant at amino acid 172 that is associated with a 2-fold decrease in sensitivity to β-glucosides and is linked to alcohol dependence10, 14, 15.
S. aureus bone sialoprotein-binding protein (Bbp) is an allelic variant of SdrE (Peacock et al., 2002).
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