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After trafficking through the secretory pathway, fully matured PrPC localizes to cholesterol-rich lipid rafts, and cycles through the endocytic pathway (review in [5]).
After trafficking in the blood or lymphatic vessels, tumor cells tend to form emboli extravasating into distant organs or lymph nodes [ 1, 326].
Malarek estimates that trafficking in women generates about $12bn£6.6bnbn) a year, making it the third largest money-making venture in the world, after trafficking in weapons and drugs.
Similarly, lentiviruses, appear to readily infect skin-derived DC and retain their capacity to present viral antigens after trafficking suggesting that both the virus and the antigen influence antigen presentation by different DC subsets [2], [6], [20].
Our results demonstrate that after trafficking with endosomes, eGFP NPRA routed with lysosome.
Mucin domains are heavily sialylated with significant consequences for protein conformation during and after trafficking (Table 4).
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