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Loading and first maintenance vancomycin doses were both incorrect in 37.4% (58/155) of patients before and 13.4% (19/142) after calculator implementation, p<0.001.
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In a post dated Oct. 30, the day after calculators were required to appear under the law, a parent posted the results of one calculator's findings.
In total, 707 patients were included in the study; 410 received gentamicin (195 before and 215 after the calculator implementation) and 297 received vancomycin (155 before and 142 after the calculator implementation).
You may be surprised to learn that your hot performing fund wasn't so hot after the calculator spits out the true cost of owning the fund taxes, management fees, trading costs.
After the calculator hacking community discovered the independent tool Ndless (which allows for third-party development on TI's platform), TI has spent the last year updating its OS to prevent downgrading to version 1.1, which is necessary to run Ndless.
Correct vancomycin loading doses increased from 41.9% (65/155) before to 67.6% (96/142) after the calculator implementation, OR=2.89, p<0.001.
The whole vancomycin initiation regimen was correct (both loading and first maintenance doses were correct) in 23.9% (37/155) of patients before and 47.9% (68/142) after the calculator implementation, OR=2.93, p<0.001 (table 4).
The same tests were also used to measure the significance of the difference between the number of correct doses among different patient groups before and after the calculators.
Two-sample t test was used to evaluate the difference in the age, BMI and CrCl of patients, before and after the calculators.
χ Analysis and Fisher's exact test were used to assess the significance of the difference between the patients' gender, ethnicity and prescriber specialty, before and after the calculators' implementation.
Keith Gumbinger, HSH.com's vice president, designed the calculator after helping his son walk through various scenarios while applying for a mortgage.
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