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As specificity engineering cases accumulate, understanding the mechanisms of the specificity determination will increase.
And when teens learn to push themselves to grow, they begin to accumulate understanding of what it takes to be a productive, independent adult.
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Accumulated understanding derived from murine systems is increasingly becoming more translatable to human immunology and disease pathology.
This accumulating understanding of the mechanism of action of estrogen led ultimately to the design of antiestrogenic agents that work by virtue of their interaction with the ER; these drugs have come to be known as selective estrogen receptor modulators (SERMs).
In recent years, there has been an accumulating understanding of their role as signaling molecules (Atashi et al., 2015).
Recognizing the useful knowledge held by health system actors allows health policy and systems researchers to access a greater breadth of such knowledge, including practical, moral, and cultural wisdom drawn from lived experiences and accumulated understanding of health system realities [ 20] (Case studies 1 to 3).
Moreover, underexpression of LKB1 in ccRCC complements the accumulating understanding that kidney cancer is a disease of cell metabolism with AMPK underactivation as the common molecular hub which was only demonstrated for other less common subtypes of RCC until now (Linehan et al, 2010).
Ultimately, it will be ideal for a knowledge-based automated composite design expert system be established, which would include accumulated understandings and models developed in this area.
But, in this campaign, she has quietly adjusted her public image to emphasize the work she puts in, the accumulated effort of understanding the relationship between public policy and a person's life.
Knowledge as a process (Berkes 2012) inevitably entails some tension between traditionally accumulated ways of understanding environmental phenomenon and structuring social behaviour, and new sources of knowledge acquired through learning, experimentation and sharing.
We propose conducting empirical studies to accumulate real evidence for understanding the context of RAs from essential types of stakeholders.
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