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We concentrated our focus mostly on novel candidate genes outside the MHC region, although our 133 screened genes did include the above mentioned previously screened genes with exception of TNFα and IL2 (see Supplementary Table S1).
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As mentioned previously, above results should not be interpreted as representative of causal relationships strictly speaking.
However, as mentioned previously, above a certain concentration, which might be different for different cell types, the two largest AAV Rep proteins have cytostatic or even cytotoxic properties.
The canonical text, mentioned previously, is Brooks Jr., The Mythical Man-Month (above, n. 4).
CITED2, as mentioned previously is the only known p63 target gene of the above listed genes [ 40].
The above result of 50% ASC-CM was quoted and the assay procedure was the same as mentioned previously.
As mentioned previously in Eqs.
China, as mentioned previously, 58.
Except for PI 3-kinases, the above mentioned mediators have previously been reported involved in S100A4-induced signaling [ 10, 12, 15], and the seemingly conflicting results may be explained by cell line specific differences, for instance in expression of cell surface receptors or intracellular signal transduction molecules.
For the above mentioned effect, it has previously been shown that trastuzumab, by binding the HER-2 receptor, increases internalization and degradation of the latter, which might augment the amount of HER-2-derived peptides available for loading to MHC class I [24], [25].
The potential of genomic selection in the above mentioned hybrid population was previously found to substantially depend on genetic relatedness [ 11].
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