Sentence examples for ATP outflow from inspiring English sources
Accordingly, Bekar et al. (2008) have shown in vitro that DBS is associated with an increase of ATP outflow within the thalamus, resulting in an accumulation of adenosine, which, in turn, depresses excitatory transmission through A1 receptor activation.
Importantly, recent in vitro data reported that DBS is associated with an increase of ATP outflow within both thalamic and cortical slices, resulting in an accumulation of adenosine, which in turn depresses excitatory transmission through A1 receptor activation (Bekar et al., 2008).
(C) ATP efflux in biofilms.
The initial step in this purinergic regulation is ATP release from outflow-pathway cells by mechanisms unknown.
Heart failure may lead to hypoperfusion and hypooxygenation of tissues and this is often exacerbated by central and obstructive sleep apnoeas associated with recurrent episodes of systemic hypoxia which triggers release of ATP within the CNS circuits controlling sympathetic outflow.
In summary, this study provides direct evidence that in developing heart failure actions of extracellular ATP within the RVLM presympathetic circuits contribute to increased sympathetic outflow, facilitate LV remodelling and worsen the development of heart failure.
We now tested whether altered ATP release might also be a mediator of ouabain's effect on outflow facility.
Our guiding hypothesis is that ecto-enzymatic conversion of extracellular ATP to adenosine activates A(1) adenosine receptors, reducing resistance to aqueous humor outflow and intraocular pressure.
To test whether adenosine triphosphate (ATP) release links cytoskeletal remodeling with release of matrix metalloproteinases (MMPs), regulators of outflow facility and intraocular pressure.ATP release was measured by luciferin-luciferase. Ecto-ATPases from transformed human trabecular meshwork (TM) cells (TM5) and explant-derived TM cells were identified by RT-PCR.
The additional H+ outflow required for maintenance of the intracellular pH in the presence of weak acids dissipates extra ATP, decreasing cytosolic ATP pool.
