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ATP generation in ECs has been shown to derive mainly from glucose uptake and utilization [3], [4], [5].
Upon activation, AMPK phosphorylates a wide array of downstream effectors to enhance ATP generation and reduce ATP expenditure (Hardie, 2011).
The rest of the ATP demand was assumed to be provided by respirative ATP generation.
MRMs inhibit the process of electron transfer and ATP generation from electron transport chain leading to incomplete respiration and reduced ATP generation.
Generally, elevated serum lactate reflects that the aerobic ATP generation is insufficient for the required ATP generation and needs to be supplemented with anaerobic ATP generation.
Fuel usage for ATP generation is dependent on the conditions of the body.
Necrosis is characterized by mitochondrial swelling, loss of Δψm, and impaired OXPHOS and ATP generation.
Adenosine 5′-triphosphate (ATP) generation is an essential biological reaction for all living cells.
The elaborate membrane architecture of mitochondria is a prerequisite for efficient respiration and ATP generation.
Glutamine is a very versatile nutrient feeding into many pathways for ATP generation, redox homeostasis, and biosynthesis [22].
Elevated aerobic glycolysis in cancer cells serves many purposes, ensuring ATP generation without reliance on oxygen availability.
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CEO of Professional Science Editing for Scientists @ prosciediting.com