An initial effort involved the synthesis of a library of 18 740 TALEN pairs that span the human genome.
Clearly, river catchmentwide assessment would be preferable despite the initial effort involved.
Their initial efforts involved listening with Mars Odyssey, an American craft already in orbit, and with various Earth-bound radio telescopes.
The amount of effort involved — a coffee every couple of months, for example — is well worthwhile, especially as it also provides a chance to talk about projects and new technologies.
But, given their potential to exert a stabilising influence on the world economy and to shrink the widening and disproportional gap between the rich and the poor, we believe the effort involved must be absolutely worthwhile.
The chief barrier to the implementation of a fully vMDT is the fact that, in oncological practice, there are very few precedents for this way of working and, given the innate conservatism of many professionals, it may be difficult to persuade participants that the effort involved in learning the skills required is a worthwhile investment.
Adams made an initial effort to bring Jefferson into the cabinet and involve him in shaping foreign policy, but Jefferson declined the offer, preferring to retain his independence.
Studies show that plants increase employee productivity and health, so it's a worthwhile benefit for everyone involved.
Hearst's initial effort to bolster Seventeen will involve some subtraction.
The initial effort yielded a long, unwieldy research questionnaire, one that included the pet questions of everyone involved in drafting the survey.
The government's initial efforts to help Alstom involved just such a method, but the deal was resisted in Brussels.Even after approving a revised deal, Mario Monti, the competition commissioner, is following the rehabilitation effort closely.
