Sentence examples for A substitutions from inspiring English sources

(Left) We compared the proportion of C > T (and G > A) substitutions in the CpC (GpG) context (mutational signature for UV [ Alexandrov et al., 2013 ]) between melanomas and breast cancers (controls).

These included (a) substitutions at the G171 in blade 4, (b) mutations in blades 2 6 of β-propeller 1, and (c) mutations in β-propellers 2, 3 and 4.

Although C to T and G to A substitutions, which are caused by deaminated cytosine residues, occur at a rate of 4.5 to 5.9%, other error rates are at most 0.3% (fig. S4).

Mutant c-Jun contained (S63/S73 and T91/T93→ A substitutions).

Namely, 4 of the 5 mutation hotspots (i.e. 25, 26, 54 and 281) involved A substitutions and were located in loops of the predicted secondary structure.

Comparison with Japanese HAV A10 revealed 222C to G or T substitution in 8/12 cases of severe disease and 222C to G or T and 392G to A substitutions in 5/7 and 4/7 cases of mild disease, respectively, although the nucleotide sequences in this study showed high homology (93.6% 100%).

All π-A substitutions resulted a broader absorption spectrum with a redshift up to 2500 nm which is a significant improvement compared to the vast majority of reported sensitizers.

To explore the significance of ETS co-occupancy for selection of off-targets, we used DamID to determine the targets of an NKX2-5 mutant carrying tyrosine alanine (Y-A) substitutions in the YRD because this mutant does not interact with ELK1/4.

Sequence analysis of nef and vpu from three lymphoid tissues revealed a high percentage of G-to-A-substitutions. Our results show that while the presence of HCCH and SLQYLA domains are critical in vivo, there may exist APOBEC3 negative reservoirs that allow for low levels of viral replication and persistence but not disease.

Hence, our results with a. a. substitutions fit the proposed TLR2-Pam2CSK4 interacting model.

Most sequences contained both C->T and G->A substitutions, although there were a few with just one type of transition is addressed below).