Sentence examples for A substantive challenge from inspiring English sources

The party could avoid the national embarrassment of a Paladino candidacy and mount a substantive challenge to the Democratic nominee, Andrew Cuomo.

It's by no means bulletproof; there are lots of moving parts to these arguments, and the fact that we've had debt bubbles in periods of low inequality is a substantive challenge to their hypothesis.

Kay Redfield Jamison Washington Daphne Merkin replies: Kay Jamison's insultingly reductionist characterization of both my work and my life in no way offers a substantive challenge to what was a thoughtful, if critical, review.

At least this is true if embodied cognition is to mark a significant departure from, and pose a substantive challenge to, traditional cognitive science and associated philosophical views of the mind.

The government's main problem, though, the substantive challenge, is the many complications associated with going there.

Even if one succeeds in developing a positive theory of moral epistemology in light of which moral knowledge might be possible, the substantive challenge of showing that knowledge has actually been secured remains formidable.

The most substantive challenge they appear willing to make toward the party's right-most wing is banalities about inflation.

They are home to some of his biggest political and substantive challenges, including a depressed economy, a disenchanted middle class and a disdain for government highlighted by the Tea Party movement.

5 The total syntheses of 3′-aminoacyl and 3′-peptidyl-RNA represent substantive challenges for organic chemists; 2c, d therefore, a central focus of our research is the de novo synthesis of these derivatives.

"Substantive challenges remain".

Definitions, classification, and documentation are substantive challenges to comprehensive event capture.