Sentence examples for A substantial difficulty for from inspiring English sources

The time points of all participant-related actions to be taken during the study period are presented in table 1. Retaining participants in a clinical trial of long-term duration represents a substantial difficulty for research teams.

The additional germ line cells occupy locations near somatic cells of interest throughout the trunk of the worm, which poses a substantial difficulty for annotation approaches that rely on location-based features alone.

While T. gondii has an intron rich genome and, consequently, presents substantial difficulty for gene prediction programs to properly identify gene coding regions, in C. parvum there are almost no introns and gene prediction is rather straightforward [ 20].

In daily listening environments, noise corrupts speech and creates substantial difficulty for various applications such as hearing aid design and automatic speech recognition.

The membrane itself may play a role but creates substantial difficulties for structural studies.

Distortions due to reverberation have a direct impact on the modulation spectrum, and they also cause substantial difficulties for human listeners [15],[15].

Unfortunately this evolution as not without notable difficulties: issues surrounding the cost of products, the lack of support from large corporations and choice of platform resulted in substantial difficulties for educators in the assessment of appropriate technology.

In addition, signing the TPP agreement can also be expected to cause substantial difficulties for the social services, telecommunications services and healthcare services industries, which in turn could lead to a reduction in job opportunities, particularly for young people (Wang 2014).

Despite their similar beginnings, the women's lives take very different turns and a lifetime of discrimination, lost wages, lack of family recognition, and more add up to create substantial difficulties for Jackie.

But retooling the fast-growing industry of factor production posed substantial difficulties, for several reasons.

The authors concluded that especially the dose assessment of CT examinations pose substantial difficulties for non-radiologists.