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A single instance can, perhaps, lead to justified generalization.
A single instance of Autodock was mapped to a single CPU core in every case.
A single instance of sexual assault is one too many".
"There has never been a single instance in the last 17 years that [the Pakistanis] at any level have ever claimed we violated the line of control," he says.
Have you read of a single instance in the past three years where the bank made a profit on a foreclosure?As I understand it, one of the main reasons for the housing bubble's inflation was that this model of mortgage issuance ceased to exist by the early 2000s with the advent of residential mortgage-backed securities (RMBSs).
Ramesh Babu and Ramesh Babu (1999): a single instance with 50 rectangles to be placed.
Growing up in Baltimore in the 1960s and 1970s, I experienced not a single instance of blatant anti-Semitism.
But there is yet another more compelling fact: in all the thousands of naked mole rats that have lived and died in research labs and zoos over the past several decades, not a single instance of spontaneous cancer has been recorded1.
Replicate experiments were pooled together, with neighbouring peaks (two peak maximums within 500 bp or 1000 bp) flagged as a single instance of a region.
As someone who has followed the story since the 1980s, I can't remember a single instance.
**There was a single instance of methylprednisolone being prescribed at a dose of 1000 mg; the reason for this dose was not recorded in the notes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com