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The attendant effects were analyzed which if used allow SCV costs׳ significant minimization.
A significant drawback of the RMSD minimization (although not exclusive to it) is found in its weighting scheme.
A significant strong negative correlation has been observed between error minimization capacity and GC content of both housekeeping (Rs = −0.541, P < 0.001) and tissue-specific genes (Rs = −0.499, P < 0.001) in Arabidopsis (Supplementary Tables S6 S9 contain Arabidopsis housekeeping and tissue-specific homologous genes and their corresponding GC3 and error minimization values).
A significant strong negative correlation (Rs = −0.606, P < 0.001) has been observed between error minimization capacity and GC content of housekeeping genes in rice.
Likewise, such cost effective hybrid thermochromic coatings could play a significant role in the minimization of air conditioning load and thus energy consumption in both building and automotive sectors.
However, since the execution of even a local minimization takes a significant amount of computational resources, we decided to perform separate local minimizations.
The results of the minimizations provide a significant complement to experimental efforts and aid in the understanding of the enzymatic profile of cytidine deaminase.
The choice of the minimization algorithm has a significant impact on the organization of the computation of restraints.
Evidently, the minimization of conformations can have a significant impact on some of our observations, and, where relevant, we therefore also discuss the effects of local minimization.
We also observed a significant governing principle of protein folding in terms of the minimization of the sum of the all pairs shortest path (APSP) for all the residues of the protein.
Results: IOMA is shown to successfully predict the metabolic state of human erythrocytes (compared to kinetic model simulations), showing a significant advantage over the commonly used methods flux balance analysis and minimization of metabolic adjustment.
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