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A severe drawback arises when a gyroscope with this non-collocated design is employed, since the readout is active during force-feedback.
However, graphene also suffers from a severe drawback: it is gapless, implying that a graphene based field-effect transistor is not within reach.
"This is a severe drawback," says Andy Hall, a pharmacogenomics researcher and director of the Northern Institute for Cancer Research at the University of Newcastle-upon-Tyne in England.
The occurrence of significant degradation by β-scission reaction is a severe drawback affecting the classical procedure of polypropylene (PP) functionalization in the melt with maleic anhydride (MAH) or derivatives and free radical initiators.
However, a severe drawback of the autofocus algorithms is that they are only capable of removing one-dimensional azimuth phase errors.
However, this extension mechanism has a severe drawback: the semantic meaning of the extended features or properties is only defined by free text.
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In our study, these techniques were found to be equally safe and effective in the treatment of BPH without any severe drawbacks as long as patients were selected according to risk factors.
However, this leads to an even more severe drawback, unmet demand.
A severe technical drawback of geothermal heat pumps (GHPs) is the fact that the nominal operating temperature available for domestic space heating is typically in the region of 50 °C.
Third, unlike frameshift mutations caused by mis-splicing, no severe drawback would be expected if cleavage occurs at a slightly (±5 nt) different position.
One severe drawback of neural network is that its optimal structure is not explicit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com