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Filamin A modifies HCN1, but not HCN2 or HCN4 channel activity and distribution on the cell membrane [29].
For the TLR5 G22A SNP, the best fit model was the additive model, where having each copy of A modifies the risk of developing IBD in an additive form.
We leveraged the multivariate nature of our data to identify the direction of genetic interactions by testing each pair of genes (A and B) for one of two directional relationship models: A modifies the phenotype of B, or B modifies the phenotype of A. Moreover, we assigned a sign to the relationship, which indicates whether the modification is of an alleviating or aggravating nature.
Similar(57)
Since JAM-A has been implicated in leukocyte extravasation, we investigated whether the absence of JAM-A modifies the inflammatory reaction of the dystrophic skeletal muscle.
The second objective was to find out whether SP-A from the hypophase associates with DPPC/Re-LPS-mixed monolayers as well as with DPPC monolayers (13, 14) and whether SP-A modifies lipid lateral organization of such monolayers.
(A modified version of 2000a).
A modified handbrake serves as the accelerator.
A modified NASA telescope could detect dangerous radioactive materials.
A modified Latin alphabet was adopted in 1922.
A modified treatment is reported.
A modified version of this story appears at Stanford Health Policy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com