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'A major problem' is correct and usable in written English
You can use it when you need to describe a significant issue, difficulty, or challenge. For example, "Air pollution is becoming a major problem in many large cities."
Exact(60)
A major problem was parking.
A major problem is affordability.
A major problem was down Swansea's left.
A major problem derives from enzyme biodistribution.
"They are a major problem".
Rabies is a major problem in China.
Lipodystrophy is still a major problem.
"Otherwise there could be a major problem".
Impunity is a major problem in Mexico.
It's a major problem for Al Qaeda".
We have got a major problem.
More suggestions(15)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com