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A KoKo DigiDoser spirometer (nSpire Health, Inc., Longmont, CO, USA) was used to administer all challenge aerosols, according to the five-breath method 25, 27.
Spirometry was measured as per international guidelines [ 148] using a KOKO spirometer (inSpire Health Inc. USA and FVCC, FEV1, FEV1/FVC and FEF25 75 reported.
Spirometry tests were performed using a Koko spirometer (KoKo®; Pulmonary Data Services Instrumentation; Louisville, CO) while participants were seated in their hospital room.
Briefly, lung function measurements were conducted using a Koko Spirometer and software with a desktop portable device (PDS Instrumentation, Louisville, USA), according to American Thoracic Society guidelines [ 20].
Bronchial allergen challenge was performed with D. pteronyssinus, birch, or five grass mixture allergens (Stallergenes SA, Antony Cedex, France) at different concentrations (0.1, 1.0, 10.0, and 33.3 IR/mL) using a KoKo DigiDoser nebulizer (Sunrise Medical, Somerset, PA, USA) [ 28].
Hypertonic saline (4.5%) was inhaled for doubling time periods and a inspiratory-expiratory FVL was measured, in duplicate, 60 seconds after each saline dose using a KoKo K323200 Spirometer (Technipro, North Parramatta, Australia).
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As a child, Koko developed a deep love of gospel, blues, and chocolate (hence her nickname).
I first met Nicola when artist Matthew Stone was assisting him on a project and they scouted me as a model outside Koko, a music venue in Camden.
Forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) was determined using a portable spirometer connected to a computer (KoKo Spirometer and KoKo DigiDoser; Pulmonary Data Service Instrumentation , Inc Louisville, Kentucky, USA), calibrated in the morning and after every 10th measurement.
Lee and Carter's dreams will continue to materialize this coming fall when they headline a show at Koko, a short walk from Carter's apartment.
The first cover, in October of 1978, featured a photograph Koko had taken of herself in a mirror.
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