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A few alignments were not reliable and discarded from further analysis.
This implies that only a few alignments need to be provided as examples of manual editing to properly train the classifier.
For a sequence to be classified as Y-linked with the chromosome quotient it must have many alignments from males, and zero or a few alignments from females.
Thus far only a few alignments have been produced among organismal anatomy ontologies, such as those between mice and humans (8, 9) and multiple anatomy ontologies [Uberon (10, 11)].
We increased the number of Y chromosome sequences identified by allowing a few alignments from the female sequence data, as long as there were many more alignments from the male sequence data.
Nevertheless, there were a few alignments (typically from M2 and PB1-F2 proteins) where FLU was significantly worse than the HIV-specific models or general models, e.g. LG, or JTT.
Similar(54)
A few alignment algorithms output site-specific scores that allow the selection of high-confidence regions.
Furthermore, to increase sensitivity, a few alignment errors are permitted.
The sequences were confirmed using Sanger tags, which had exact matches except for a few alignment gaps near the ends of the tags.
This distribution shows that a majority of probes have few alignments on the genome, generally one or two.
When larger datasets become available, we expect the total running time of an all-against-all alignment to increase more than quadratic with dataset size: We have shown above that a large fraction of the total running time stems from a few 'hard' alignments which, in turn, correspond to a few trees in the dataset that are large and, in particular, have high out degrees.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com