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A considerable disadvantage of boosting in adolescence is that there is currently no infrastructure for routine vaccination in this age group, particularly in the developing world.
A considerable disadvantage of intraspecific calibrations is that they will often produce date estimates with a larger degree of uncertainty than those made using external calibrations.
A considerable disadvantage of classical Schistosoma diagnostics is the persistence of serologic markers and egg shedding after successful treatment.
A considerable disadvantage of manual volume correction is the significantly higher measurement time, which has been demonstrated in this study and is in agreement with human studies (15, 17).
Estimates of Alexios's total force vary from 5,500 6,500 (Haldon) to some 8,000 10,000 (Birkenmeier), but it is clear that he was at a considerable disadvantage against Bryennios; not only was his force considerably smaller, but also far less experienced than Bryennios's veterans.
This prejudice puts startups at a considerable disadvantage.
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The first task was the defense of Saudi Arabia, which General Schwarzkopf's command took on from a position of considerable disadvantage.
Ultimately, the choice not to share instrumentation may place an organization at considerable disadvantage.
Within the context of separate Aboriginal social networks, considerable disadvantage, and a high prevalence of smoking, young girls use smoking to attain status and assert their group membership and Aboriginal identity.
Meso-tetrahydroxyphenyl chlorin is a powerful photosensitiser, but has the considerable disadvantage that it is necessary to wait up to 4 days after giving the drug before delivering the light.
Because the VOW business model is the same as a traditional brokerage to sell houses being cut out of listings put them at a considerable competitive disadvantage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com