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A considerable challenge in the proposed merger, which was first reported by the online edition of The Wall Street Journal, is reconciling the two firms' compensation systems.
A considerable challenge in the treatment of cancer in these patients is the ability to achieve proper chemotherapy dosing.
A considerable challenge in the analysis is constituted by the presence of heterozygous mutations, which in M2s are expected to be 2/3 of the mutant sites.
A considerable challenge in the efforts to translate in vivo optical imaging findings from laboratory animals (i.e., rodents) to humans will be the need to perform similar set(s) of studies in nonhuman primates (NHP).
A considerable challenge in critical care medicine is therefore to rescue ARDS patients by means of ventilatory therapy in the short term and to optimize morbidity in the long term [ 10].
A considerable challenge in Hb research is deciphering how evolution has harnessed the helical folds of the M and S lineages ("3/3" helical arrangement) and the T lineage ("2/2" helical arrangement) to adapt to various environments and metabolic needs.
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At a more practical level, a considerable challenge lies in identifying optimal parameters.
This extensive LD presents a considerable challenge, however, in identifying the IPD-causative polymorphism.
Sleep problems in children with common psychiatric disorders present a considerable challenge for clinicians in developing effective diagnosis and treatment strategies.
This combination will pose a considerable challenge to managers in seeking to embed recent progress and run a single, safe and decent centre".
Although designing these proteins is still a considerable challenge, future advances in rational protein design and a deeper understanding of their photoactivation mechanisms will allow the development of the next generation of optogenetic techniques.
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