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A complimentary study of the ecological niche differentiation in these populations shows that the demes of chimpanzees found in this study also occupy significantly different niches [ 53], suggesting that environmental variation contributes to driving the differentiation of these populations.
Genetic studies are less susceptible to confounding than observational epidemiology [21] and may offer a complimentary study design [22].
CEUS was never performed as a sole imaging study but rather as a complimentary study to MDCT or MRI.
However, a complimentary study by Jeffrey et al in which transgenic mice expressing PrPC only in astrocytes did succumb to disease, albeit following an extended incubation period, suggests that the mechanisms of cell death are complicated, and not restricted to a neuronal response [ 50].
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We performed a complimentary pharmacogenetic study to investigate germline polymorphisms of genes involved in 5-fluorouracil (5-FU) and irinotecan pathways and their potential association with clinical outcomes and toxicities from neoadjuvant chemoradiation in patients with rectal cancer treated in a prospective genotype-directed study.
The complimentary study examined the function of stromal PHD2 in regulating tumour metastasis.
Furthermore, in another complimentary study we found significant associations between genetic differentiation in these three demes and environmental variation across the study area [ 56], which led us to conclude that these populations likely follow a pattern of isolation-by-environment [ 57], a relationship between populations that arises as a result of local adaptation to different environments.
For comparison, complimentary studies were conducted with water-soluble electron donors (acetate and dextrose).
Two complimentary studies in the Gulf Coastal Plain of the southeastern US were designed to test whether harvest intensity (level of biomass removal) could have a negative long-term impact on site productivity.
Complimentary studies using cancer-prone Trp53+/− mice demonstrate F-FDG injections of 0.75 MBq (10 mGy whole body dose) increased the latency of some types of cancers.
Importantly, complimentary studies with SK inhibitor SKI-II and the SK2-specific inhibitor ABC resulted in significant inhibition of virus infection, further confirming the siRNA experiments.
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