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Durations of mechanical ventilation and hospitalization were shorter among patients treated with doripenem than among those treated with a comparator; between-group differences in ICU stay were not statistically significant (Table 2).
Their approach makes an assumption that any node w is capable of playing the role of a "comparator" in differentiating between responses from two of its neighbors, u and v.
The use of rescue medications (RD), although not used as an outcome comparator between the use of single drugs and the combination was clearly restricted to twice a week and did not reveal differences between groups.
In the perceptual literature, JND represents the smallest detectable change by which a subject can reliably discriminate between a comparator and an original stimulus.
In clinical trials, outcomes may be measured as: the mean difference in the total score on a given scale between active treatment and comparator groups; the delay to reaching specific milestones; or the percentage of 'responders' to treatment compared with a comparator treatment group or placebo.
The quantifications were also conducted by HPLC as a comparator and a good correlation between both analytical methods was observed, thus validating the spectrometric method (see the Supporting Information for detailed UV/Vis absorbance data and HPLC chromatograms).
For example, one might expect a very small effect between a treatment and an active comparator, and a larger effect between placebo and treatment.
In a 12-month comparator study between pioglitazone and rosiglitazone combined with metformin, no body mass index (BMI) changes were observed in either group.
This is an important comparator to identify differences between cell populations from different culture batches.
The focus on 3- and 5-year rates leads to the common comparator for between model types for absolute survival rates, and absolute differences in survival rates by treatment.
EPICS (Enlarged Prostate International Comparator Study) was a short-term direct comparator trial between dutasteride (0.5 mg) and finasteride (5 mg) in men with BPH (Gilling et al. 2005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com