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This novel culture system may be applicable as a cellular platform for fundamental studies in cell biology and tissue engineering applications.
Most importantly the niche was pointed out for serving as a cellular platform for the expansion of stem cells that could potentially be exploited for therapeutic tissue/organ neogenesis.
We examined the anti-fibrotic effects of a variety of herbal constituents using a cellular platform, the LTC-14 cells, which retained essential characteristics and morphologies of primary PSCs, by means of various biochemical assays including cell viability test, real-time polymerase chain reaction and Western blotting analysis.
CD44 is a transmembrane glycoprotein that participates in many cellular processes including regulation of cell division, survival, migration, and adhesion [ 11] through the binding of its major ligand, hyaluronic acid, and by acting as a cellular platform for growth factors and heparan-sulphate proteoglycans.
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Thus, this chip technique is a promising cellular platform for tissue engineering or regenerative medicine research, pharmacological and toxicological studies, and fundamental studies in cell biology.
Therefore, Jurkat-KI-R5 cells represent a much-needed cellular platform to support future HIV research.
Cyanobacteria represent an almost ideal cellular platform for biotechnological production.
Further, these new data identify the basis of an in vivo cellular platform critical for membrane recruitment and regulation of Nav1.5.
On the unit torn apart by Chipworks (A1778), an Intel mobile cellular platform is present, including two RF transceivers, power management and modem.
Our work demonstrates that patient-specific iPSCs can provide an exciting new cellular platform for such screening (Grskovic et al, 2011).
Together, this study is the first to demonstrate alterations of human vascular smooth muscle contractility and pharmacological responsiveness in biomimetic soft, fibrous environments with a cellular array platform.
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