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Talks on a BWC protocol broke down last summer, when the U.S. delegation pulled out of negotiations due to concerns that enforcement measures--such as lab inspections--might compromise national security and threaten biotech companies (Science, 20 July, p. 414).
On the other hand, a vertex in a connected graph incurs a BWC of zero if none of the neighbors of the vertex go through it for their shortest path(s) to any other vertex in the graph.
We observe that vertices 0, 6, and 7 that do not lie on the shortest path for any two vertices in the graph have a BWC of zero each and also have LCCDC value of zero each.
In other words, a vertex sustains a BWC value of zero if it is either a stub vertex (has a degree of 1: that is connected to only one other vertex) or there exists a link between any two neighbors of the vertex.
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Our hypothesis is that nodes with a high degree, but low local clustering coefficient, are more likely to be on the shortest paths of several node pairs and are likely to incur a larger BWC value.
In addition, such a high-degree vertex with a lower LCC might be on the shortest path of several other pairs of vertices (especially, for those vertices that are in the 2-hop and 3-hop neventuallyd), eventually contributing to a higher BWC for the vertex.
With the assumption of a higher BWC the computed concentration of O2Hb decreased and the computed concentration of HHb increased.
In this study, rcStO2 was calculated based on the probably incorrect assumption of a constant BWC of 75% throughout the study period.
We have previously described [ 16] that introducing a water term into equations describing the relation between the absorption coefficient, μa, and the slope of the decrease in light intensity using multi-distance FD-NIRS resulted in minor changes in StO2-measurements of the neonatal head if a constant BWC of 90% was assumed.
Section 3 introduces the local clustering coefficient-based degree centrality (LCCDC) metric and justifies its proposal as an alternate for BWC with a motivating example.
As a result, vertex 5 is more likely to occupy a relatively larger fraction of the shortest path between any two vertices and incur a relatively larger BWC value compared to vertex 4 (even though vertex 4 has a larger EVC value).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com