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Fig. 2 Master model featuring metal teeth Fig. 3 Duplication of the master model in silicone.
We applied genome engineering to delete 3p in lung cells, causing decreased proliferation rescued in part by chromosome 3 duplication.
The AR population of 22Rv1 is heterogeneous consisting of a constitutive active truncated AR (ARΔLBD), and a mutated - substitution of tyrosine for histidine (H875Y) in the LBD and/or an in-frame exon 3 duplication (E3DM) in the DNA-binding domain - AR.
Major exclusion criteria as: (1) No sufficient data of CCL3L1 GCN distribution among the cohorts; (2) Reviews; (3) Duplication of previous studies.
Given the synteny surrounding some orthologues of each gain (Fig. 3), duplication events are the most parsimonious explanation.
Some other intronic variations in TP53 were reported to affect disease risk previously and the most widely studied one is TP53 intron 3 duplication polymorphism (rs17878362) [ 5, 25].
Similar(44)
One cuticle protein (FBgn0033869, 33 duplications), Actin (3 duplications) and vitellogenin (4 duplications) were found to be tandem duplicated in the D. pulex genome.
There are at least four major mechanisms to produce duplicate genes: (1) genome duplication, (2) tandem gene duplication, (3) segmental duplication and (4) transpositional duplication [31].
Soybean CS expansion occurred in 66 duplication events.
Identified ATP1A2 duplication was confirmed by Real Time PCR.
Fig. 3 a ATP1A2 duplication in SHM patient obtained by MLPA assay.
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