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ATP binding draws loop11 and loop9 closer together; causing (1) tilting of most of the motor domain not contacting the MT towards the nucleotide-binding site, (2) rotation, translation, and extension of helix-α6 which we propose contributes to force generation, and (3) allows neck linker docking and biases movement of the 2nd head towards the MT plus end.
Thomas D. Thacher 2nd, head of Thacher Associates, a corporate investigations company, said that as Mayor Michael R. Bloomberg tries to persuade Albany to give him direct control of city schools, "There is clearly a need to also reform the watchdog function".
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