Your English writing platform
Discover LudwigSuggestions(1)
Exact(4)
Suppose, if the number of factors are 2, with 2 trail runs, then α value is calculated as 22/4 = 1.414.
2) Trail Making Test, Part A and B [ 23]: these tests measure processing speed and executive function, respectively.
We assessed global cognition using the Mini-Mental State Examination (MMSE) and executive functions using the: 1) Stroop Test; 2) Trail Making Test (Part B) and 3) Digits Verbal Span Backwards Test.
Paper-and-pencil tests: (1) Rey-Osterrieth Complex Figure Test, testing visuospatial memory; (2) Trail making test A and B, primarily testing psychomotor speed; (3) Symbol digit modalities test, testing psychomotor speed and (4) Verbal fluency test, testing verbal semantic and phonological fluency.
Similar(52)
Of these, only TRAIL receptor 1 (TRAIL-R1, DR4) and TRAIL receptor 2 (TRAIL-R2, DR5) mediate apoptosis as they contain a functional death domain (DD) required for apoptosis signaling.
To this end, alternative pathways, such as the one activated by death receptors including Fas/Apo-1, or tumour necrosis factor-related apoptosis-inducing ligand Receptor 1 (TRAIL-R1) and TRAIL Receptor 2 (TRAIL-R2), are being explored for cancer treatment.
HBV-specific T cells up-regulate TRAIL death receptor 2 (TRAIL-R2), which renders them susceptible to apoptosis by TRAIL-expressing NK cells.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to its receptors, TRAIL-receptor 1 (TRAIL-R1) and TRAIL-receptor 2 (TRAIL-R2), leading to apoptosis by activation of caspase-8 and the downstream executioner caspases, caspase-3 and caspase-7 (caspase-3/7).
Noteworthy, this effect was protein 53 (p53) independent and was mediated by TRAIL-receptor 2 (TRAIL-R2) upregulation, demonstrating the applicability of this approach in p53-defective tumors.
Both TRAIL receptors 1 and 2 (TRAIL-R1 and TRAIL-R2) contain a conserved cytoplasmic region termed the death domain (DD) that is required for TRAIL-induced apoptosis.
TRAIL mediates apoptosis through two death receptors, TRAIL-receptor 1 (TRAIL-R1, DR4, TNFRSF10A) and TRAIL-receptor 2 (TRAIL-R2, DR5, TNFRSF10B).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com