An example of a complex assay is KRAS_1 and KRAS_2, which interrogate 2 different nucleotide positions within codon 12 and together identify all codon 12 amino acid changes.
3) Interrogate available databases for physical interactions between the proteins of interest.
50 Artists Interrogate 25 Years of Police Brutality.
The admission that MI5 interrogated a British resident, Binyam Mohamed, after the CIA had provided a graphic description of the way he was being tortured.
The second investigation, Operation Hinton, which examined the way in which MI5 interrogated Binyam Mohamed at a time when he was being tortured, also ended without any charges being brought.
This processor, although originally designed for active measurements with a 252Cf interrogating source, has been successfully used passively (without 252Cf source) for systems with inherent neutron sources such as fissile systems of plutonium.
The two target SRRM2 cDNAs were amplified using TaqMan assay (∼120 bp sequence) Hs00909897_m1, interrogating exon 2 3 boundary, and Hs00249492_m1, interrogating exons 12 13 boundary.
The ATTILE1R interrogates 1,683,620 unique genome locations with 25mer oligonucleotides distributed across the Arabidopis genome at an average spacing of ∼35 bp [15].
The corresponding probe (ILMN_1747227) interrogated the 3'UTR region of the ADORA1 transcript (NM_000674.1) and provided a fold change of 2.9 and a FDR of 0%.
These include employing strict computational assay design algorithms [22], [23], interrogating amplified targets with specific extenders or probes [24] [27], and/or validating amplified target sizes [28], [29].
