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2 Grading is significantly different between the two cohorts of patients: HER2+ patients are mainly G3, while HER2- patients are mostly G2 (P = 0.01).
The pre-publication history for this paper can be accessed here: 1 Mean ± SD for continues variables with normal distribution, geometric mean (lower, upper SD) when distribution was not normal 2 Grading based on WHO Expert report, reference 27. 3 Cut-offs based on reference 28.
Interrater reliability in the pilot phase (two reviewers), across 150 pairwise comparisons, was 63% at the per-concept level, and in only one instance (0.7%) did the two reviewers differ by 2 grading steps (i.e., 0, Not addressed/absent, and 2, Adequate).
Similar(56)
Grade 2, Grade 1, or -- the most desirable -- export grade.
2) Grade inflation.
Data were collected as 0 (no PVR), 1 (grade A), 2 (grade B), 3 (grade C), and 4 (grade D).
All specimens were evaluated to the normal, grade 1, grade 2, grade 3, grade 4, grade 5 groups.
The histopathological criteria gave the RPN2-positive group grade 2: 2, grade 1: 30, grade 0: 2, vs the RPN2-negative group grade 3: 5, grade 2: 4, grade 1: 6 (P<0.001).
They included 125 Grade II, 2 Grade IIIa, 9 Grade IIIb and 3 Grade IVa complications (Table 3).
grade 0: normal; grade 1: very slight; grade 2: slight; grade 3: moderate; grade 4: severe.
The majority of patients presented with high grade neoplasms (grade 3: 47.8% grade 2: 43.5% grade 1: 8.7%).
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CEO of Professional Science Editing for Scientists @ prosciediting.com